In vivo measurement of ALDH2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1-(13)C]pyruvate

To date, measurements of the activity of aldehyde dehydrogenase-2 (ALDH2), a critical mitochondrial enzyme for eliminating certain cytotoxic aldehydes in the body and a promising target for drug development, have been largely limited to in vitro methods. Recent advancements in magnetic resonance spe...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Josan, Sonal, Xu, Tao, Yen, Yi-Fen, Hurd, Ralph, Ferreira, Julio, Chen, Che-Hong, Mochly-Rosen, Daria, Pfefferbaum, Adolf, Mayer, Dirk, Spielman, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634870/
https://ncbi.nlm.nih.gov/pubmed/23225495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2897
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items