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Permeabilization of the Blood-Brain Barrier via Mucosal Engrafting: Implications for Drug Delivery to the Brain

Utilization of neuropharmaceuticals for central nervous system(CNS) disease is highly limited due to the blood-brain barrier(BBB) which restricts molecules larger than 500Da from reaching the CNS. The development of a reliable method to bypass the BBB would represent an enormous advance in neurophar...

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Bibliografiske detaljer
Main Authors: Bleier, Benjamin S., Kohman, Richie E., Feldman, Rachel E., Ramanlal, Shreshtha, Han, Xue
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634848/
https://ncbi.nlm.nih.gov/pubmed/23637885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061694
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