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A Study of the Mechanism of the Chaperone-like Function of an scFv of Human Creatine Kinase by Computer Simulation

A new application of antibodies is to use them as macromolecular chaperones. Protein antigens usually have multiple epitopes, thus, there may be a plurality of antibodies binding to one antigen. However, not all antibodies that bind to one antigen could act as a chaperone. Experiments show that some...

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Detalhes bibliográficos
Main Authors: Feng, Jianyu, Guo, Hong, Li, Sen, Lu, Tun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634753/
https://ncbi.nlm.nih.gov/pubmed/23637984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062147
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