Engineering production of functional scFv antibody in E. coli by co-expressing the molecule chaperone Skp

Single-chain variable fragment (scFv) is a class of engineered antibodies generated by the fusion of the heavy (V(H)) and light chains (V(L)) of immunoglobulins through a short polypeptide linker. ScFv play a critical role in therapy and diagnosis of human diseases, and may in fact also be developed...

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Dettagli Bibliografici
Autori principali: Wang, Rongzhi, Xiang, Shuangshuang, Feng, Youjun, Srinivas, Swaminath, Zhang, Yonghui, Lin, Mingshen, Wang, Shihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818579/
https://ncbi.nlm.nih.gov/pubmed/24224158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2013.00072
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