CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim

Extensive studies on CD4(+) CD25(+) regulatory T (Treg) cells suggest that they are important in regulating immune responses. However, mechanisms of peripheral Treg cell homeostasis are unknown. We found that stromal cells isolated from secondary lymphoid organs such as spleen and lymph nodes could...

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Detalhes bibliográficos
Main Authors: Kashiwakura, Yuji, Sakurai, Daisuke, Kanno, Yumiko, Hashiguchi, Masaaki, Kobayashi, Ayano, Kurosu, Akira, Tokudome, Shogo, Kobata, Tetsuji, Kojima, Hidefumi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634538/
https://ncbi.nlm.nih.gov/pubmed/23278598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12054
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