CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim

Extensive studies on CD4(+) CD25(+) regulatory T (Treg) cells suggest that they are important in regulating immune responses. However, mechanisms of peripheral Treg cell homeostasis are unknown. We found that stromal cells isolated from secondary lymphoid organs such as spleen and lymph nodes could...

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Bibliographische Detailangaben
Hauptverfasser: Kashiwakura, Yuji, Sakurai, Daisuke, Kanno, Yumiko, Hashiguchi, Masaaki, Kobayashi, Ayano, Kurosu, Akira, Tokudome, Shogo, Kobata, Tetsuji, Kojima, Hidefumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634538/
https://ncbi.nlm.nih.gov/pubmed/23278598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12054
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