NFκB attenuates IL-5 production and upregulates T-box transcription factors in Th2-like T cells

IL-5 plays important roles in eosinophil differentiation, expansion, and recruitment. The regulation of IL-5 seems critical for the treatment of eosinophil-mediated allergic reactions. However, the precise mechanisms for IL-5 regulation remain unknown. In this study, we investigated how IL-5 product...

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Main Authors: Hashiguchi, Masaaki, Kobayashi, Ayano, Kashiwakura, Yuji, Kojima, Hidefumi, Kanno, Yumiko, Kurosu, Akira, Tokudome, Shogo, Kobata, Tetsuji
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2013
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973803/
https://ncbi.nlm.nih.gov/pubmed/23934330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9585-z
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