A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival

The mechanisms that allow the maintenance of immunological memory remain incompletely defined. Here we report that tumor necrosis factor receptor (TNFR)-associated factor (TRAF) 1, a protein recruited in response to several costimulatory TNFR family members, is required for maximal CD8 T cell respon...

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Autori principali: Sabbagh, Laurent, Srokowski, Cathy C., Pulle, Gayle, Snell, Laura M., Sedgmen, Bradley J., Liu, Yuanqing, Tsitsikov, Erdyni N., Watts, Tania H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693726/
https://ncbi.nlm.nih.gov/pubmed/17116875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602919103
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