Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe

BACKGROUND & AIMS: HFE and transferrin receptor 2 (TFR2) are each necessary for the normal relationship between body iron status and liver hepcidin expression. In murine Hfe and Tfr2 knockout models of hereditary hemochromatosis (HH), signal transduction to hepcidin via the bone morphogenetic pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Corradini, Elena, Rozier, Molly, Meynard, Delphine, Odhiambo, Adam, Lin, Herbert Y., Feng, Qi, Migas, Mary C., Britton, Robert S., Babitt, Jodie L., Fleming, Robert E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634343/
https://ncbi.nlm.nih.gov/pubmed/21745449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.077
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