Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe

BACKGROUND & AIMS: HFE and transferrin receptor 2 (TFR2) are each necessary for the normal relationship between body iron status and liver hepcidin expression. In murine Hfe and Tfr2 knockout models of hereditary hemochromatosis (HH), signal transduction to hepcidin via the bone morphogenetic pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Corradini, Elena, Rozier, Molly, Meynard, Delphine, Odhiambo, Adam, Lin, Herbert Y., Feng, Qi, Migas, Mary C., Britton, Robert S., Babitt, Jodie L., Fleming, Robert E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634343/
https://ncbi.nlm.nih.gov/pubmed/21745449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.077
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