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Identification of Metabolic Engineering Targets through Analysis of Optimal and Sub-Optimal Routes

Identification of optimal genetic manipulation strategies for redirecting substrate uptake towards a desired product is a challenging task owing to the complexity of metabolic networks, esp. in terms of large number of routes leading to the desired product. Algorithms that can exploit the whole rang...

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Autors principals: Soons, Zita I. T. A., Ferreira, Eugénio C., Patil, Kiran R., Rocha, Isabel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633962/
https://ncbi.nlm.nih.gov/pubmed/23626708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061648
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