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Random sampling of elementary flux modes in large-scale metabolic networks

Motivation: The description of a metabolic network in terms of elementary (flux) modes (EMs) provides an important framework for metabolic pathway analysis. However, their application to large networks has been hampered by the combinatorial explosion in the number of modes. In this work, we develop...

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Detalhes bibliográficos
Main Authors: Machado, Daniel, Soons, Zita, Patil, Kiran Raosaheb, Ferreira, Eugénio C., Rocha, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436828/
https://ncbi.nlm.nih.gov/pubmed/22962475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts401
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