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Random sampling of elementary flux modes in large-scale metabolic networks

Motivation: The description of a metabolic network in terms of elementary (flux) modes (EMs) provides an important framework for metabolic pathway analysis. However, their application to large networks has been hampered by the combinatorial explosion in the number of modes. In this work, we develop...

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Autori principali: Machado, Daniel, Soons, Zita, Patil, Kiran Raosaheb, Ferreira, Eugénio C., Rocha, Isabel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436828/
https://ncbi.nlm.nih.gov/pubmed/22962475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts401
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