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Evolutionary programming as a platform for in silico metabolic engineering

BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...

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Bibliografiske detaljer
Main Authors: Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327682/
https://ncbi.nlm.nih.gov/pubmed/16375763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-308
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