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Evolutionary programming as a platform for in silico metabolic engineering

BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...

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Hlavní autoři: Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327682/
https://ncbi.nlm.nih.gov/pubmed/16375763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-308
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