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Evolutionary programming as a platform for in silico metabolic engineering

BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...

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Detalhes bibliográficos
Main Authors: Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327682/
https://ncbi.nlm.nih.gov/pubmed/16375763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-308
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