Natural computation meta-heuristics for the in silico optimization of microbial strains

BACKGROUND: One of the greatest challenges in Metabolic Engineering is to develop quantitative models and algorithms to identify a set of genetic manipulations that will result in a microbial strain with a desirable metabolic phenotype which typically means having a high yield/productivity. This cha...

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Autores principales: Rocha, Miguel, Maia, Paulo, Mendes, Rui, Pinto, José P, Ferreira, Eugénio C, Nielsen, Jens, Patil, Kiran Raosaheb, Rocha, Isabel
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612012/
https://ncbi.nlm.nih.gov/pubmed/19038030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-499
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