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Evolutionary programming as a platform for in silico metabolic engineering

BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both in terms of structure and regulation, it...

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Autori principali: Patil, Kiran Raosaheb, Rocha, Isabel, Förster, Jochen, Nielsen, Jens
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1327682/
https://ncbi.nlm.nih.gov/pubmed/16375763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-308
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