Hypothalamic Inhibition of Acetyl-CoA Carboxylase Stimulates Hepatic Counter-Regulatory Response Independent of AMPK Activation in Rats

BACKGROUND: Hypothalamic AMPK acts as a cell energy sensor and can modulate food intake, glucose homeostasis, and fatty acid biosynthesis. Intrahypothalamic fatty acid injection is known to suppress liver glucose production, mainly by activation of hypothalamic ATP-sensitive potassium (K(ATP)) chann...

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Autores principales: Santos, Gustavo A., Pereira, Vinícius D., Roman, Erika A. F. R., Ignacio-Souza, Leticia, Vitorino, Daniele C., de Moura, Rodrigo Ferreira, Razolli, Daniela S., Torsoni, Adriana S., Velloso, Licio A., Torsoni, Marcio A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633841/
https://ncbi.nlm.nih.gov/pubmed/23626844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062669
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