Acetyl-CoA carboxylase 1–dependent lipogenesis promotes autophagy downstream of AMPK

Autophagy, a membrane-dependent catabolic process, ensures survival of aging cells and depends on the cellular energetic status. Acetyl-CoA carboxylase 1 (Acc1) connects central energy metabolism to lipid biosynthesis and is rate-limiting for the de novo synthesis of lipids. However, it is unclear h...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Gross, Angelina S., Zimmermann, Andreas, Pendl, Tobias, Schroeder, Sabrina, Schoenlechner, Hannes, Knittelfelder, Oskar, Lamplmayr, Laura, Santiso, Ana, Aufschnaiter, Andreas, Waltenstorfer, Daniel, Ortonobes Lara, Sandra, Stryeck, Sarah, Kast, Christina, Ruckenstuhl, Christoph, Hofer, Sebastian J., Michelitsch, Birgit, Woelflingseder, Martina, Müller, Rolf, Carmona-Gutierrez, Didac, Madl, Tobias, Büttner, Sabrina, Fröhlich, Kai-Uwe, Shevchenko, Andrej, Eisenberg, Tobias
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690696/
https://ncbi.nlm.nih.gov/pubmed/31209110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007020
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi