NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through redox regulation of NF-κB activity

Although reactive oxygen species (ROS) produced by NADPH oxidase are known to regulate inflammatory responses, the impact of ROS on intracellular signaling pathways is incompletely understood. In these studies, we treated wild-type and p47(phox) deficient mice with LPS to investigate mechanisms by w...

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Huvudupphovsmän: Han, Wei, Li, Hui, Cai, Jiyang, Gleaves, Linda A., Polosukhin, Vasiliy V., Segal, Brahm H., Yull, Fiona E., Blackwell, Timothy S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633681/
https://ncbi.nlm.nih.gov/pubmed/23530143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201809
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