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NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through redox regulation of NF-κB activity

Although reactive oxygen species (ROS) produced by NADPH oxidase are known to regulate inflammatory responses, the impact of ROS on intracellular signaling pathways is incompletely understood. In these studies, we treated wild-type and p47(phox) deficient mice with LPS to investigate mechanisms by w...

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書誌詳細
主要な著者: Han, Wei, Li, Hui, Cai, Jiyang, Gleaves, Linda A., Polosukhin, Vasiliy V., Segal, Brahm H., Yull, Fiona E., Blackwell, Timothy S.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633681/
https://ncbi.nlm.nih.gov/pubmed/23530143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201809
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