NADPH Oxidase Limits Innate Immune Responses in the Lungs in Mice

BACKGROUND: Chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide anion and downstream reactive oxidant intermediates (ROIs), is characterized by recurrent bacterial and fungal infections and by excessive inflammati...

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Hlavní autoři: Segal, Brahm H., Han, Wei, Bushey, Jennifer J., Joo, Myungsoo, Bhatti, Zahida, Feminella, Joy, Dennis, Carly G., Vethanayagam, R. Robert, Yull, Fiona E., Capitano, Maegan, Wallace, Paul K., Minderman, Hans, Christman, John W., Sporn, Michael B., Chan, Jefferson, Vinh, Donald C., Holland, Steven M., Romani, Luigina R., Gaffen, Sarah L., Freeman, Michael L., Blackwell, Timothy S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838778/
https://ncbi.nlm.nih.gov/pubmed/20300512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009631
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