NADPH Oxidase Limits Innate Immune Responses in the Lungs in Mice

BACKGROUND: Chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide anion and downstream reactive oxidant intermediates (ROIs), is characterized by recurrent bacterial and fungal infections and by excessive inflammati...

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Main Authors: Segal, Brahm H., Han, Wei, Bushey, Jennifer J., Joo, Myungsoo, Bhatti, Zahida, Feminella, Joy, Dennis, Carly G., Vethanayagam, R. Robert, Yull, Fiona E., Capitano, Maegan, Wallace, Paul K., Minderman, Hans, Christman, John W., Sporn, Michael B., Chan, Jefferson, Vinh, Donald C., Holland, Steven M., Romani, Luigina R., Gaffen, Sarah L., Freeman, Michael L., Blackwell, Timothy S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838778/
https://ncbi.nlm.nih.gov/pubmed/20300512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009631
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