NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury

Recruitment of neutrophils and release of reactive oxygen species are considered to be major pathogenic components driving acute lung injury (ALI). However, NADPH oxidase, the major source of reactive oxygen species in activated phagocytes, can paradoxically limit inflammation and injury. We hypothe...

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Detalhes bibliográficos
Main Authors: Davidson, Bruce A., Vethanayagam, R. Robert, Grimm, Melissa J., Mullan, Barbara A., Raghavendran, Krishnan, Blackwell, Timothy S., Freeman, Michael L., Ayyasamy, Vanniarajan, Singh, Keshav K., Sporn, Michael B., Itagaki, Kiyoshi, Hauser, Carl J., Knight, Paul R., Segal, Brahm H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563868/
https://ncbi.nlm.nih.gov/pubmed/23296708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202410
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