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THE RHODOPSIN-TRANSDUCIN COMPLEX HOUSES TWO DISTINCT RHODOPSIN MOLECULES
Upon illumination the visual receptor rhodopsin (Rho) transitions to the activated form Rho*, which binds the heterotrimeric G protein, transducin (G(t)) causing GDP to GTP exchange and G(t) dissociation. Using succinylated concanavalin A (sConA) as a probe, we visualized native Rho dimers solubiliz...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633645/ https://ncbi.nlm.nih.gov/pubmed/23458690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.02.014 |
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