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Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin

Transitory binding between photoactivated rhodopsin (Rho* or Meta II) and the G protein transducin (Gt-GDP) is the first step in the visual signaling cascade. Light causes photoisomerization of the 11-cis-retinylidene chromophore in rhodopsin (Rho) to all-trans-retinylidene, which induces conformati...

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Bibliographic Details
Main Authors: Jastrzebska, Beata, Golczak, Marcin, Fotiadis, Dimitrios, Engel, Andreas, Palczewski, Krzysztof
Format: Artigo
Language:Inglês
Published: The Federation of American Societies for Experimental Biology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630779/
https://ncbi.nlm.nih.gov/pubmed/18827025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.07-114835
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