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PHOSPHOLIPIDS ARE NEEDED FOR PROPER FORMATION, STABILITY AND FUNCTION OF THE PHOTOACTIVATED RHODOPSIN-TRANSDUCIN COMPLEX

Heterotrimeric G proteins become activated after they form a catalytically active complex with activated G protein-coupled receptors (GPCRs) and GTP replaces GDP on the G protein α subunit. This transient coupling can be stabilized by nucleotide depletion, resulting in an empty-nucleotide G-protein-...

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Autori principali: Jastrzebska, Beata, Goc, Anna, Golczak, Marcin, Palczewski, Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753473/
https://ncbi.nlm.nih.gov/pubmed/19413332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900284x
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