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RHODOPSIN-TRANSDUCIN HETEROPENTAMER: THREE-DIMENSIONAL STRUCTURE AND BIOCHEMICAL CHARACTERIZATION

The process of vision is initiated when the G protein-coupled receptor, rhodopsin (Rho), absorbs a photon and transitions to its activated Rho* form. Rho* binds the heterotrimeric G protein, transducin (G(t)) inducing GDP to GTP exchange and G(t) dissociation. Using nucleotide depletion and affinity...

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Bibliographic Details
Main Authors: Jastrzebska, Beata, Ringler, Philippe, Lodowski, David, Moiseenkova-Bell, Vera, Golczak, Marcin, Müller, Shirley A., Palczewski, Krzysztof, Engel, Andreas
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210324/
https://ncbi.nlm.nih.gov/pubmed/21925606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.08.016
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