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The Molecular Basis of β-Thalassemia
The β-thalassemias are characterized by a quantitative deficiency of β-globin chains underlaid by a striking heterogeneity of molecular defects. Although most of the molecular lesions involve the structural β gene directly, some down-regulate the gene through distal cis effects, and rare trans-actin...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2013
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633182/ https://ncbi.nlm.nih.gov/pubmed/23637309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a011700 |
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