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The molecular basis of beta-thalassemia in Thailand: application to prenatal diagnosis.

To enable the prenatal diagnosis of beta-thalassemia by direct detection of the mutant beta-globin genes, we have determined the spectrum of mutations causing this disease in Thailand. The techniques employed included a combination of synthetic oligonucleotide probe hybridization, direct sequencing...

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Autores principales: Thein, S L, Winichagoon, P, Hesketh, C, Best, S, Fucharoen, S, Wasi, P, Weatherall, D J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683861/
https://ncbi.nlm.nih.gov/pubmed/2393018
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