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Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator
Desformylflustrabromine (dFBr; 1) and desformylflustrabromine-B (dFBr-B; 2) have been previously isolated from natural sources, and the former has been demonstrated to be a novel and selective positive allosteric modulator of α4β2 nicotinic acetylcholine (nACh) receptors. The present study describes...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633077/ https://ncbi.nlm.nih.gov/pubmed/17604168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.047 |
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