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Single-Dose Safety, Tolerability, and Pharmacokinetics of the Antibiotic GSK1322322, a Novel Peptide Deformylase Inhibitor

GSK1322322 is a potent inhibitor of peptide deformylase, an essential bacterial enzyme required for protein maturation. GSK1322322 is active against community-acquired skin and respiratory tract pathogens, including methicillin-resistant Staphylococcus aureus, multidrug-resistant Streptococcus pneum...

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Bibliografski detalji
Glavni autori: Naderer, Odin J., Dumont, Etienne, Zhu, John, Kurtinecz, Milena, Jones, Lori S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632897/
https://ncbi.nlm.nih.gov/pubmed/23403431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01779-12
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