Safety, Tolerability, and Efficacy of GSK1322322 in the Treatment of Acute Bacterial Skin and Skin Structure Infections

GSK1322322 represents a new class of antibiotics that targets an essential bacterial enzyme required for protein maturation, peptide deformylase. This multicenter, randomized, phase IIa study compared the safety, tolerability, and efficacy of GSK1322322 at 1,500 mg twice daily (b.i.d.) with that of...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Corey, Ralph, Naderer, Odin J., O'Riordan, William D., Dumont, Etienne, Jones, Lori S., Kurtinecz, Milena, Zhu, John Z.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249383/
https://ncbi.nlm.nih.gov/pubmed/25136015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03360-14
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