Safety, Tolerability, and Efficacy of GSK1322322 in the Treatment of Acute Bacterial Skin and Skin Structure Infections

GSK1322322 represents a new class of antibiotics that targets an essential bacterial enzyme required for protein maturation, peptide deformylase. This multicenter, randomized, phase IIa study compared the safety, tolerability, and efficacy of GSK1322322 at 1,500 mg twice daily (b.i.d.) with that of...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Corey, Ralph, Naderer, Odin J., O'Riordan, William D., Dumont, Etienne, Jones, Lori S., Kurtinecz, Milena, Zhu, John Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249383/
https://ncbi.nlm.nih.gov/pubmed/25136015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03360-14
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