Effect of H(2) Blockade and Food on Single-Dose Pharmacokinetics of GSK1322322, a Peptide Deformylase Inhibitor Antibacterial

GSK1322322 is first in a new class of antibiotics, peptide deformylase inhibitors, and is active against multidrug-resistant respiratory and skin pathogens. Part 1 of this phase 1, randomized, single-dose (1,000 mg) study in 20 healthy volunteers compared the relative bioavailability of three differ...

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Bibliografiska uppgifter
Huvudupphovsmän: Naderer, Odin J., Dumont, Etienne, Zhu, John, Kurtinecz, Milena, Jones, Lori S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716165/
https://ncbi.nlm.nih.gov/pubmed/23529727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02505-12
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