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Diaphragm Atrophy and Contractile Dysfunction in a Murine Model of Pulmonary Hypertension

Pulmonary hypertension (PH) causes loss of body weight and inspiratory (diaphragm) muscle dysfunction. A model of PH induced by drug (monocrotaline, MCT) has been extensively used in mice to examine the etiology of PH. However, it is unclear if PH induced by MCT in mice reproduces the loss of body w...

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Detalhes bibliográficos
Main Authors: Ahn, Bumsoo, Empinado, Hyacinth M., Al-Rajhi, Monsour, Judge, Andrew R., Ferreira, Leonardo F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632558/
https://ncbi.nlm.nih.gov/pubmed/23614054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062702
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