Cancer-specific requirement for BUB1B/BubR1 in human brain tumor isolates and genetically transformed cells

To identify new candidate therapeutic targets for Glioblastoma multiforme (GBM), we combined functional genetics and GBM network modeling to identify kinases required for the growth of patient-derived brain tumor initiating cells (BTICs), but which are dispensable to proliferating human neural stem...

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Detalhes bibliográficos
Main Authors: Ding, Yu, Hubert, Christopher G., Herman, Jacob, Corrin, Philip, Toledo, Chad M., Skutt-Kakaria, Kyobi, Vazquez, Julio, Basom, Ryan, Zhang, Bin, Risler, Jennifer K., Pollard, Steven M., Nam, Do-Hyun, Delrow, Jeffery J., Zhu, Jun, Lee, Jeongwu, DeLuca, Jennifer, Olson, James M., Paddison, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632446/
https://ncbi.nlm.nih.gov/pubmed/23154965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0353
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