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Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice
The establishment of a polarized cellular morphology is essential for a variety of processes including neural tube morphogenesis and the development of the brain. Cdc42 is a Ras-related GTPase that plays an essential role in controlling cell polarity through the regulation of the actin and microtubu...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Higher Education Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632363/ https://ncbi.nlm.nih.gov/pubmed/23150167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2098-2 |
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