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Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice

The establishment of a polarized cellular morphology is essential for a variety of processes including neural tube morphogenesis and the development of the brain. Cdc42 is a Ras-related GTPase that plays an essential role in controlling cell polarity through the regulation of the actin and microtubu...

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Autors principals: Peng, Xu, Lin, Qiong, Liu, Yang, Jin, Yixin, Druso, Joseph E., Antonyak, Marc A., Guan, Jun-Lin, Cerione, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: Higher Education Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632363/
https://ncbi.nlm.nih.gov/pubmed/23150167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2098-2
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