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Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells

BACKGROUND AND PURPOSE: Oestrogen receptor alpha (ERα) binds to different ligand which can function as complete/partial oestrogen-agonist or antagonist. This depends on the chemical structure of the ligands which modulates the transcriptional activity of the oestrogen-responsive genes by altering th...

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Detalhes bibliográficos
Main Authors: Sengupta, S, Obiorah, I, Maximov, PY, Curpan, R, Jordan, VC
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632247/
https://ncbi.nlm.nih.gov/pubmed/23373633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12122
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