Delayed triggering of oestrogen induced apoptosis that contrasts with rapid paclitaxel-induced breast cancer cell death

BACKGROUND: Oestrogen (E(2)) induces apoptosis in long-term E(2)-deprived MCF7 cells (MCF7:5C). Taxanes have been used extensively in the treatment of early and advanced breast cancer. We have interrogated the sequence of events that involve the apoptotic signalling pathway induced by E(2) in compar...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Obiorah, I, Sengupta, S, Fan, P, Jordan, V C
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
Translational Therapeutics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960622/
https://ncbi.nlm.nih.gov/pubmed/24548860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.50
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