Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

Defects in ribosome biogenesis trigger stress response pathways, which perturb cell proliferation and differentiation in several genetic diseases. In Diamond–Blackfan anemia (DBA), a congenital erythroblastopenia, mutations in ribosomal protein genes often interfere with the processing of the intern...

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Detalhes bibliográficos
Main Authors: Preti, Milena, O'Donohue, Marie-Françoise, Montel-Lehry, Nathalie, Bortolin-Cavaillé, Marie-Line, Choesmel, Valérie, Gleizes, Pierre-Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632142/
https://ncbi.nlm.nih.gov/pubmed/23482395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt160
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