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Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells

It is generally assumed that, in mammalian cells, preribosomal RNAs are entirely processed before nuclear exit. Here, we show that pre-40S particles exported to the cytoplasm in HeLa cells contain 18S rRNA extended at the 3′ end with 20–30 nucleotides of the internal transcribed spacer 1. Maturation...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rouquette, Jacques, Choesmel, Valérie, Gleizes, Pierre-Emmanuel
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187937/
https://ncbi.nlm.nih.gov/pubmed/16037817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600752
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