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Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

Our knowledge of the functions of metazoan ribosomal proteins in ribosome synthesis remains fragmentary. Using siRNAs, we show that knockdown of 31 of the 32 ribosomal proteins of the human 40S subunit (ribosomal protein of the small subunit [RPS]) strongly affects pre–ribosomal RNA (rRNA) processin...

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Autori principali: O’Donohue, Marie-Françoise, Choesmel, Valérie, Faubladier, Marlène, Fichant, Gwennaële, Gleizes, Pierre-Emmanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935573/
https://ncbi.nlm.nih.gov/pubmed/20819938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201005117
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