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Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA
Defects in ribosome biogenesis trigger stress response pathways, which perturb cell proliferation and differentiation in several genetic diseases. In Diamond–Blackfan anemia (DBA), a congenital erythroblastopenia, mutations in ribosomal protein genes often interfere with the processing of the intern...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632142/ https://ncbi.nlm.nih.gov/pubmed/23482395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt160 |
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