Gradual processing of the ITS1 from the nucleolus to the cytoplasm during synthesis of the human 18S rRNA

Defects in ribosome biogenesis trigger stress response pathways, which perturb cell proliferation and differentiation in several genetic diseases. In Diamond–Blackfan anemia (DBA), a congenital erythroblastopenia, mutations in ribosomal protein genes often interfere with the processing of the intern...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Preti, Milena, O'Donohue, Marie-Françoise, Montel-Lehry, Nathalie, Bortolin-Cavaillé, Marie-Line, Choesmel, Valérie, Gleizes, Pierre-Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632142/
https://ncbi.nlm.nih.gov/pubmed/23482395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt160
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