A far-upstream (−70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration

SOX9 encodes a transcription factor that presides over the specification and differentiation of numerous progenitor and differentiated cell types, and although SOX9 haploinsufficiency and overexpression cause severe diseases in humans, including campomelic dysplasia, sex reversal and cancer, the mec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mead, Timothy J., Wang, Qiuqing, Bhattaram, Pallavi, Dy, Peter, Afelik, Solomon, Jensen, Jan, Lefebvre, Véronique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Gene Regulation, Chromatin and Epigenetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632127/
https://ncbi.nlm.nih.gov/pubmed/23449223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt140
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