Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes

The transcription factor Sox9 is necessary for early chondrogenesis, but its subsequent roles in the cartilage growth plate, a highly specialized structure that drives skeletal growth and endochondral ossification, remain unclear. Using a doxycycline-inducible Cre transgene and Sox9 conditional null...

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Bibliografiske detaljer
Main Authors: Dy, Peter, Wang, Weihuan, Bhattaram, Pallavi, Wang, Qiuqing, Wang, Lai, Ballock, R. Tracy, Lefebvre, Véronique
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306603/
https://ncbi.nlm.nih.gov/pubmed/22421045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.12.024
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