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Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

Sox5 and Sox6 encode Sry-related transcription factors that redundantly promote early chondroblast differentiation. Using mouse embryos with three or four null alleles of Sox5 and Sox6, we show that they are also essential and redundant in major steps of growth plate chondrocyte differentiation. Sox...

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Detalhes bibliográficos
Main Authors: Smits, Patrick, Dy, Peter, Mitra, Srijeet, Lefebvre, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172159/
https://ncbi.nlm.nih.gov/pubmed/14993235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312045
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