SOX9 keeps growth plates and articular cartilage healthy by inhibiting chondrocyte dedifferentiation/osteoblastic redifferentiation

Cartilage is essential throughout vertebrate life. It starts developing in embryos when osteochondroprogenitor cells commit to chondrogenesis, activate a pancartilaginous program to form cartilaginous skeletal primordia, and also embrace a growth-plate program to drive skeletal growth or an articula...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Haseeb, Abdul, Kc, Ranjan, Angelozzi, Marco, de Charleroy, Charles, Rux, Danielle, Tower, Robert J., Yao, Lutian, Pellegrino da Silva, Renata, Pacifici, Maurizio, Qin, Ling, Lefebvre, Véronique
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2021
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923381/
https://ncbi.nlm.nih.gov/pubmed/33597301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019152118
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