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Effects of minocycline plus tPA combination therapy after focal embolic stroke in type 1 diabetic rats

BACKGROUND AND PURPOSE: Post-stroke hyperglycemia is associated with resistance to tissue plasminogen activator (tPA) reperfusion, higher risk of intracerebral hemorrhage (ICH) and worse neurological outcomes. In this study we asked whether minocycline combined with intravenous tPA may ameliorate in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Xiang, Lo, Eng H., Wang, Xiaoying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632085/
https://ncbi.nlm.nih.gov/pubmed/23422086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.000309
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