Modeling Ewing sarcoma tumors in vitro with 3D scaffolds

The pronounced biological influence of the tumor microenvironment on cancer progression and metastasis has gained increased recognition over the past decade, yet most preclinical antineoplastic drug testing is still reliant on conventional 2D cell culture systems. Although monolayer cultures recapit...

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Main Authors: Fong, Eliza Li Shan, Lamhamedi-Cherradi, Salah-Eddine, Burdett, Emily, Ramamoorthy, Vandhana, Lazar, Alexander J., Kasper, F. Kurtis, Farach-Carson, Mary C., Vishwamitra, Deeksha, Demicco, Elizabeth G., Menegaz, Brian A., Amin, Hesham M., Mikos, Antonios G., Ludwig, Joseph A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631678/
https://ncbi.nlm.nih.gov/pubmed/23576741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221403110
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