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Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma

Three-dimensional tumor models accurately describe different aspects of the tumor microenvironment and are readily available for mechanistic studies of tumor biology and for drug screening. Nevertheless, these systems often overlook biomechanical stimulation, another fundamental driver of tumor prog...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Santoro, Marco, Lamhamedi-Cherradi, Salah-Eddine, Menegaz, Brian A., Ludwig, Joseph A., Mikos, Antonios G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547215/
https://ncbi.nlm.nih.gov/pubmed/26240353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506684112
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