Modeling Ewing sarcoma tumors in vitro with 3D scaffolds

The pronounced biological influence of the tumor microenvironment on cancer progression and metastasis has gained increased recognition over the past decade, yet most preclinical antineoplastic drug testing is still reliant on conventional 2D cell culture systems. Although monolayer cultures recapit...

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Hlavní autoři: Fong, Eliza Li Shan, Lamhamedi-Cherradi, Salah-Eddine, Burdett, Emily, Ramamoorthy, Vandhana, Lazar, Alexander J., Kasper, F. Kurtis, Farach-Carson, Mary C., Vishwamitra, Deeksha, Demicco, Elizabeth G., Menegaz, Brian A., Amin, Hesham M., Mikos, Antonios G., Ludwig, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631678/
https://ncbi.nlm.nih.gov/pubmed/23576741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221403110
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