The Role of Activation Functions 1 and 2 of Estrogen Receptor-α for the Effects of Estradiol and Selective Estrogen Receptor Modulators (SERMs) in Male Mice

Estradiol (E2) is important for male skeletal health and the effect of E2 is mediated via estrogen receptor (ER)-α. This was demonstrated by the findings that men with an inactivating mutation in aromatase or a non-functional ERα had osteopenia and continued longitudinal growth after sexual maturati...

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Main Authors: Börjesson, AE, Farman, HH, Engdahl, C, Koskela, A, Sjögren, K, Kindblom, JM, Stubelius, A, Islander, U, Carlsten, H, Antal, MC, Krust, A, Chambon, P, Tuukkanen, J, Lagerquist, MK, Windahl, SH, Ohlsson, C
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631300/
https://ncbi.nlm.nih.gov/pubmed/23225083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1842
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